Northern California Branch of the American Association for Laboratory Animal Science P.O.Box 60068, Palo Alto, CA 94306 | ncbaalas.org
NeuralGlider™ Cortical System
NeuralGlider-Cortical System Now Available from Actuated Medical, Inc.
Actuated Medical, Inc. (AMI) recently released the NeuralGlider-Cortical System™ for worldwide purchase. The system allows for more precise placement of neural implants and reduces cortical tissue damage in pre-clinical studies. This is AMI's third commercialized product.
"We’re excited to release the NeuralGlider™ system," said AMI president and CEO Maureen L. Mulvihill, Ph.D. "We have a great team that brought the product from concept to the market quickly, and look forward to helping neuroscientists achieve longer-term viability of recordings with less inflammatory response. Our ultimate goal is to enable the next generation of clinical neural implants."
The NeuralGlider-Cortical System™ debuted at the Society for Neuroscience’s annual meeting in November 2017. More than 30,000 scientists and researchers from around the world attend the conference each year. Researchers who use microwire arrays to gather data would benefit from the NeuralGlider-Cortical System because it uses ultrasonic vibrations to improve accurate placement of the array and reduce tissue dimpling.
The system was designed to fit most standard stereotactic frames and includes a camera with software for monitoring and recording the insertion process. To purchase the NeuralGlider-Cortical System, please call Actuated Medical at (814) 355-0003 x 117. You can also learn more at neuralglider.com
Compared to a standard control insertion (left), NeuralGlider reduced cortical surface damage and blood brain barrier leakage (IgG staining, red) at the microwire array insertion site (right). Images showed 20 μm rat cortical sections, 2 weeks after implantation with 2x4, 50 μm microwire arrays.
Ultrasonic vibration of microwire arrays during insertions with NeuralGlider significantly reduced penetration force in an agar brain model, and ex vivo rat and porcine cortex (reductions in force = 86.3%, 76.5% and 62.7%, respectively). The reduction of force correlates to a 70 – 80% reduction in cortical surface displacement/dimple during array insertion, for all tissues. * p < 0.0001; error bars = standard error of the mean. All data were normalized to the non-vibrated/control insertion average.
AALAS District 8 Action
SAVE THE DATE: 2018 District 8 Meeting May 9-11 at the The Duke Hotel, Newport Beach, CA
District 8 of the American Association for Laboratory Animal Science (AALAS) is one of eight AALAS District divisions in the United States. District 8 encompasses Alaska, Arizona, California, Hawaii, Idaho, Nevada, Montana, Oregon, Utah, and Washington. AALAS District 8 has within it's boundaries 10 of the nearly 50 affiliated Branches of the Association. Each District has 2 elected members to the AALAS Board of Trustees who, along with the Officers, serve as the governing body of AALAS. The 2017 D8 Meeting was in March.
D8 Website
The Usual Suspects
Send us your photos from NCB-AALAS events, along with brief notes on names places and happenings so we can record some history together. Our generous volunteer directors have been so busy running events like the annual Educational Symposium that we miss recording the actual day. So let's do it individually and gather pix from cell phones that were on scene! Send the goods to Carl at web services.
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